Problem 13.2

a) Draw the common setup for DESI-MS. Take care to clearly mark from where the ionizing fluid medium comes, where the sample is, and how electrically charged species are entering the analyzer.

b) What kind of instrumentation is suitable to be modified for DESI-MS? Think of different mass analyzers and ion source configurations.

c) Do you remember the typical settings of liquid and gas flow, solvents, temperatures, and angles for DESI operation? Give useful ranges.

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