Problem 14.5

a) What is SRM?

b) Suggest an SRM setup to identify the ethyl esters in the mixture described in Problem 14.4.

c) Why gives SRM improved signal-to-noise ratio as compared to the extraction of RICs from repetitive scanning data?

d) In many cases, MS/MS techniques can offer an alternative to chromatography-mass spectrometry coupling. Give an example where the MS/MS approach fails.

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