Problem 9.1

a) Explain the concept of tandem mass spectrometry.

b) Tandem MS experiments can be performed on multiple stages. What terms and acronyms are normally used to describe them?

c) Depending on the instrumental setup there are two variants of how the actual tandem MS experiment can be realized: tandem MS in space and tandem MS in time. Assign these to the list of mass analyzers below:

  1. magnetic sector:
  2. time-of-fligth:
  3. quadrupole ion trap:
  4. linear quadrupole:
  5. linear quadrupole ion trap:
  6. Fourier transform ion cyclotron resonance:

d) Try to express the criterion for your selections in c) in one sentence.

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