a) Can you draw structures of some very common MALDI matrices?
b) Try suggesting a suitable matrix. Sort out the mess in the table.
Polyacrylate Protein Oligosaccharide Polycyclic aromatic hydrocarbon Oligonucleotide Peptide Sinapinic acid alpha-Cyano-4-hydroxy-cinnamic acid 3-Hydroxypicolinic acid Dithranol LDI sufficient 2,5-Dihydroxybenzoic acidAnalyte
Matrix
c) Which sort of ions usually make up the largest portion of a matrix spectrum in positive-ion MALDI?
d) What sample layer do you prefer in MALDI preparations? Large well-shaped crystals or microcrystalline deposition?
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